LGC´S NEW GENETIC DIAGNOSTIC SERVICE DEBUTS AT INSIGHT CONFERENCE.

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LGC´S NEW GENETIC DIAGNOSTIC SERVICE DEBUTS AT INSIGHT CONFERENCE.
15 May 2006 - LGC

LGC, Europe´s leading independent analytical laboratory providing advanced chemical, biochemical and forensic analysis will be launching its new screening service of the genes associated with non-polyposis colorectal cancer with a stand at the First Conference of International Society for Gastrointestinal Hereditary Tumours, at the Hilton Newcastle Gateshead, 14 - 17 June 2005. LGC is also the primary sponsor of the UK Cancer Genetics Group meeting, a satellite meeting which will run alongside the conference on 14 June.

The new service, which will be offered to European as well as NHS customers, is the screening of the DNA mismatch repair genes hMLH1, hMSH2 and hMSH6 for variations that may be associated with HNPCC. Developed and validated in a series of blind trials with collaborator groups within and outside the NHS, including three separate colon cancer centres and the Life Knowledge Park in Newcastle, LGC´s colon cancer screening service provides the assignation and reporting of exact mutations and positions and detection of single nucleotide variants. It is an ISO 17025 and IVDD compliant service and promises rapid turnaround times to meet the individual referrer´s requirements.

Dr Paul Debenham, Director of Life Sciences at LGC, said: "The detection of inherited mutations in certain key genes linked to cancers can provide both diagnostic information about the disease in specific patients, and also enable predictive screening of family members. Using mass spectrometry combined with LGC´s proprietary analysis software, we are now able to rapidly detect exact changes in the DNA of a given patient, and simultaneously characterise the gene mutation with base change and position assigned in one single step." He added:"We are also able to analyse considerable additional DNA sequences adjacent to the actual coding DNA so as to provide a more comprehensive sweep of the gene information. We are therefore delighted to be at the First Conference of InSiGHT to launch this reliable, rapid and cost-effective gene sequence screening service."

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About: LGC
LGC is Europe's leading independent analytical laboratory providing advanced chemical, biochemical and forensic analysis, diagnostic services, DNA testing and genetic screening, research, method development, consultancy, training and analytical outsourcing. LGC operates in a diverse range of markets, in both the public and private sectors, including foods, pharmaceuticals, biotechnology, environment and chemicals and is the national measurement laboratory for chemical and biochemical analysis. LGC's services are designed to help organisations produce high quality data on which to base scientific and commercial decisions. Reference materials supplied by our market-leading distribution business, LGC Promochem, underpin the quality of measurement in many industrial sectors including pharmaceuticals. LGC Promochem distributes reference standards and ATCC biomaterials throughout Europe and in India. Growing at around 15% per annum and majority-owned by Legal & General Ventures since April 2004, LGC is based in Teddington, Middlesex, with additional laboratory facilities in Runcorn, Cheshire, in Edinburgh, Scotland and in Luckenwalde, Germany. Further offices are located in France, Germany, Italy, Poland, Spain, Sweden and India.

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