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News by Category: Medical Implants Elderly patients have a high risk of stroke within six months of a heart attack 14 April 2006 - Yale University Twenty percent of older patients who have suffered a heart attack have a one in 25 chance of being hospitalized for a stroke within six months of discharge from the hospital, according to research at Yale. More patients would refuse treatment if they knew the outcome would mean greatly impaired quality of life 13 April 2006 - Yale University More patients would refuse life-sustaining treatment if they knew the outcome would be a life of severe functional or cognitive impairment, according to a study by a Yale researcher published Thursday in the New England Journal of Medicine. Anti-fungal agent that curbed cocaine use in rodents has opposite effect in humans 11 April 2006 - Yale University Ketoconazole, an anti-fungal agent that helps curb cocaine use in laboratory rats, stimulates rather than reduces cocaine and heroin use in humans, according to a study by researchers at Yale School of Medicine. Yale researchers report on brain activity believed related to sudden infant death syndrome 08 April 2006 - Yale University Neurons thought to play a key role in sudden infant death syndrome are located near some of the largest arteries in the brain, according to a study by a Yale School of Medicine research team published in this week's issue of the journal Nature Neuroscience. Biodegradable polymers in medical applications 27 March 2006 - Rapra Technology Limited Rapra Technology, Europe's leading polymer research and test house, has secured 1.4 Million Euros of EU funding and assembled a consortium that will develop highly innovative supercritical fluid processing technology in order to make advanced multifunctional biodegradable polymer devices. Going the extra mile for specialized heart attack care 13 March 2006 - Yale University Diverting ambulances with patients suffering a heart to a hospital providing emergency angioplasty rather than a closer hospital with no ability to provide this specialized care, may be feasible for the majority of Americans, researchers at Yale School of Medicine and the University of Michigan report in Circulation. Researchers identify gene that protects against kidney stones 13 March 2006 - Yale University New Haven, Conn, Yale School of Medicine researchers report in Nature Genetics this week that they have identified a gene whose function protects the body against kidney stones. Whiplash injury much more severe when head is turned 13 March 2006 - Yale University Persons whose heads are turned at the time of a rear impact collision risk a much more serious whiplash injury with potentially chronic symptoms, and a current Yale School of Medicine study explains why. ADHD medication might also treat hyperactivity symptoms in autism 22 November 2005 - Yale University Methylphenidate, a medication used to treat attention-deficit hyperactivity disorder, may be effective in treating hyperactivity symptoms in children with autism and related pervasive developmental disorders, researchers report in the November Archives of General Psychiatry. Study has implications for vaccine design and autoimmune diseases 18 November 2005 - Yale University A report in Nature November 17 by Yale School of Medicine researchers emphasizes which cells are important in mounting an antibody response to invading microbes. Sleep apnea significantly increases risk for stroke and death 10 November 2005 - Yale University Sleep apnea, a condition where people stop breathing repeatedly while asleep, increases the risk of stroke and death, according to a study from Yale School of Medicine published November 10 in the New England Journal of Medicine. Panel at Yale will examine issues of women and health care 02 November 2005 - Yale University The Women Faculty Forum at Yale and the Yale Office of WorkLife will present a free and public forum on November 16 focusing on women's healthcare from a variety of perspectives. Study clarifies source of lymph node swelling in infections 25 October 2005 - Yale University Contrary to popular belief, lymph nodes swell due to recruitment of lymphocytes that are not specific for any given microbe, according to a report by Yale School of Medicine researchers in this week's Proceedings of the National Academy of Sciences. Cool therapy reduces brain injury and death from oxygen loss in newborns 13 October 2005 - Yale University Infants born with oxygen loss who are given an innovative therapy that lowers their entire body temperature by four degrees within the first six hours of life, have a better chance of survival and lower incidence of brain injury, according to a report in today's issue of The New England Journal of Medicine. Streamlining treatment of heart attack patients 29 September 2005 - Yale University In the first study of its kind, researchers at Yale School of Medicine show how hospitals can streamline procedures to reduce the time they take to treat heart attack patients. Overlapping genetic factors in pathological gambling and major depression 22 September 2005 - Yale University The correlation between pathological gambling and major depression in middle-aged men appears to be heavily influenced by overlapping genetic factors, according to a study by researchers at Yale School of Medicine and Washington University's School of Medicine. Yale procedure cuts recurrence of aggressive uterine cancer 22 September 2005 - Yale University A state-of-the-art treatment program developed at Yale School of Medicine increases survival from the aggressive uterine papillary serous carcinoma and spares some patients the need for additional therapy. Gene that controls the severity of asthma identified 20 September 2005 - Yale University School of Medicine researchers identified a gene prevalent in the population that controls the clinical severity of asthma, according to their report in this week's Proceedings of the National Academy of Sciences. Promising diagnostic tools for multiple sclerosis 20 September 2005 - Yale University Yale School of Medicine researchers, in collaboration with the University of Connecticut Health Center, have identified three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis patients, greatly improving potential diagnosis and treatment. Aortic aneurysm associated with decreased incidence of atherosclerosis 19 September 2005 - Yale University Oddly enough, having an aneurysm in the ascending aorta is significantly associated with decreased incidence of atherosclerosis, according to a study by Yale School of Medicine researchers published this month in Chest. Eating and body weight regulated by specific neurons 12 September 2005 - Yale University Researchers at Yale School of Medicine provide direct evidence that two parts of a neuronal system, one that promotes eating and another that suppresses eating, are critical for the acute regulation of eating and body weight, according to a study published online in the September 11 issue of Nature Neuroscience. Most embryos produced during IVF do not result in live births 08 September 2005 - Yale University Researchers at Yale School of Medicine have found that 85 percent of embryos transferred during in vitro fertilization fail to become live births, highlighting the need for improving diagnostic techniques to identify viable embryos. Inconsistent effort may be sign of attention disorder in adults and children 08 September 2005 - Yale University The adult or child who only concentrates when performing an activity in which they have a deep interest, such as playing a sport or drawing, may have 'impotence of the mind,' according to a new book by Thomas E. Brown, clinical professor of psychiatry at Yale School of Medicine. Common pesticide may reduce fertility in women 06 September 2005 - Yale University Methoxychlor, a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology. GABA halts stem cell production in the brain 01 September 2005 - Yale University Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience. Studies Find Possible Drug Targets for Improving Vascular Health 25 August 2005 - Yale University The enzyme nitric oxide synthase plays a role in peripheral vascular disease, a common disease that impairs the mobility of 25 percent of people over the age of 50, according to a Yale study in the Proceedings of the National Academy of Sciences. Brain distinguishes between nose and mouth odors 19 August 2005 - Yale University Researchers in a study in Neuron this week present the first clear evidence that the brain processes the same odorant molecule differently if it arrives through the nose rather than the mouth. Race and sex disparities in heart attack care, survival not improving 17 August 2005 - Yale University Differences based on race and sex in treatment patterns for hospitalized American heart attack patients have remained unchanged over an eight-year period, despite improvements in quality of heart attack care during this time, Emory and Yale School of Medicine researchers write in the August 18 issue of New England Journal of Medicine. Few changes in antipsychotic prescription seen after diagnosis of diabetes 09 August 2005 - Yale University Among patients being treated with antipsychotic medication, including those who were taking the most generation of drugs, a new diagnoses of diabetes did not result in substantial changes in prescription, according to a a study at Yale School of Medicine. Medication eases obsessive-compulsive symptoms 29 July 2005 - Yale University A medication used to ease symptoms of amyotrophic lateral sclerosis, or Lou Gehrig's disease, also is helpful in treating people with treatment-resistant obsessive-compulsive disorder, according to a pilot study at Yale School of Medicine. Decreased breast cancer survival associated with high TRAIL-R2 expression 25 July 2005 - Yale University High expression of TRAIL-R2, a cell surface receptor that triggers cell death, has been shown to be associated with a decrease in the survival rates of breast cancer patients according to a study published by Yale Cancer Center researchers in Clinical Cancer Research. Clinical trial tests cholesterol drug to minimize multiple sclerosis 21 July 2005 - Yale University Yale School of Medicine is participating in the first clinical trial testing atorvastatin to delay or decrease disease in patients who have experienced a first attack of multiple sclerosis. Early estrogen therapy to prevent heart disease focus of Yale study 21 July 2005 - Yale University Researchers at Yale School of Medicine and seven other national institutions are recruiting patients to participate in the Kronos Early Estrogen Prevention Study to look at the effects of estrogen on heart disease prevention. Understanding and diagnosing an inherited pain syndrome 12 July 2005 - Yale University Yale School of Medicine researchers report the first demonstration that a single mutation in a human sodium channel gene can trigger pain in people with an inherited pain syndrome known as primary erythromelalgia, according to a study published this month in the journal Brain. Protein amplification in melanoma is possible drug target 11 July 2005 - Yale University Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7. Groundbreaking study helps explain why preemie brains improve over time 27 June 2005 - Yale University Infants born prematurely and with hypoxia, inadequate oxygen to the blood, are able to recover some cells, volume and weight in the brain after oxygen supply is restored, Yale School of Medicine researchers report in Experimental Neurology. Nicotine helps Schizophrenics with attention and memory 23 June 2005 - Yale University Cigarette smoking may improve attention and short–term memory in persons with schizophrenia by stimulating nicotine receptors in the brain, according to a study by Yale School of Medicine researchers in the June issue of The Archives of General Psychiatry. Breast cancer growth regulator holds promise for more targeted treatment 22 June 2005 - Yale University Researchers at Yale School of Medicine have discovered the breast cancer growth regulator sEGFR, which may be a useful tool in monitoring a patient's responsiveness to treatment with the drug letrozole. Yale scientists find MicroRNA regulates ras cancer gene 17 March 2005 - Yale University Research in the laboratory of Assistant Professor Frank J. Slack at Yale University has identified a new way that a familiar gene is regulated in lung cancer, presenting new possibilities for diagnosis and treatment. The work is reported in March issues of the journals Cell and Developmental Cell. Boosting HIV screening can increase survival and is cost effective 09 February 2005 - Yale University Expanded HIV screening can increase patient life span, prevent the spread of the disease, and is cost effective, researchers at Yale, Harvard and the Massachusetts General Hospital report in the February 10 issue of the New England Journal of Medicine. Varicella vaccine effective on chicken pox 03 February 2005 - Yale University The varicella vaccine is almost 90 percent effective against chickenpox, but its impact on herpes zoster (shingles) is unknown and needs wider surveillance, Yale School of Medicine researchers write in today's New England Journal of Medicine perspective section. Premature births from inflammation and infection rapidly detected by proteomics technology 26 January 2005 - Yale University A combination of four proteins that result from inflammation and infection and lead to premature birth can be rapidly and accurately detected in the amniotic fluid of pregnant women using proteomics technology, Yale researchers report in two studies in the February issue of British Journal of Obstetrics and Gynecology Blocking molecule protects health of implants 20 December 2004 - Yale University Blocking a key molecule protects breast implants, permanent catheters, pacemakers, artificial joints, glucose sensors for diabetics, and other biomaterials from rejection and damage by the body, according to a study published this month in The American Journal of Pathology. Medical implants work better when you rough them up, study finds 14 June 2004 - Ohio State University Medical implants – from catheters that deliver long-term life support to joint replacements – may work better when their surfaces are on the rough side, new research suggests. World's first medical grade 17' terminal for graphics-intensive applications 09 April 2004 - Advantech UK Aimed at the market for graphics-intensive medical applications, POC-174 is based on the Mobile Intel Pentium 4 Processor-M, and is UL60601-1, EN60601 certified. POC-174's TFT LCD screen has a wide viewing angle of 170 degrees, which combined with high contrast ratio, high brightness and resolution, makes it the Point-of-care terminal of choice for applicationssuch as CT diagnosis, X-rays, PACS and DICOM. Brain area that regulates emotions is smaller in persons with bipolar disorder 18 December 2003 - Yale University A brain scanning study of adolescents and adults with bipolar disorder shows significant decrease in size in the amygdala, a brain structure that governs emotions, a Yale School of Medicine researcher has found. Clinical trial for patients with lung cancer and brain metastases 09 December 2003 - Yale University A clinical trial testing a new medication and whole brain radiation therapy for patients with non-small cell lung cancer and brain metastases is underway at Yale School of Medicine. Studies question economics of anti-psychotic and anti-depressant drugs 02 December 2003 - Yale University Two Yale studies question the economics of medications in the two most widely prescribed and costly classes of psychiatric medications. One study found that a new and more expensive anti-psychotic drug is not more effective than a less costly, older one, and the second study found that industry-associated economic studies of antidepressants favor the companies' new drugs when determining costs and cost-effectiveness. Breastfed infants show little effect when moms take anti-depressant 24 November 2003 - Yale University Most breastfed infants nurse without showing meaningful effects from their mothers taking 20-40 mg of the anti-depressant fluoxetine (Prozac) daily, according to a study by Yale researchers. Humanoid robot to aid autism diagnosis is goal of new study 17 November 2003 - Yale University A multi-disciplinary team of researchers from Yale's Child Study Center and Department of Computer Science have received a new grant from the Doris Duke Foundation to advance autism research. Premature infants benefit from group prenatal care 15 November 2003 - Yale University In a study examining the impact of group versus individual prenatal care on birth weight and gestational age, researchers at Yale and Emory Universities found that group prenatal care was associated with significantly better weight gain for preterm infants. Researchers pinpoint source of chronic pain resulting from spinal cord injury 06 November 2003 - Yale University The burning, vise-like pain experienced by most people with spinal cord injuries results from overly sensitized nerve cells; this activity can be blocked by administering specially designed molecules, according to Yale researchers. Memory enhancing drugs may worsen working memory 05 November 2003 - Yale University A new study cautions that while drugs being designed to enhance memory in the elderly seem to be effective for some types of memory, they may actually worsen working memory, according to a study by Yale researchers published Thursday in the journal Neuron. Older, chronically ill patients may not be prepared to receive prognosis 04 November 2003 - Yale University Despite previous reports concluding that patients want full disclosure about their illness, many seriously ill older persons and caregivers may not be ready or able to receive information such as life expectancy, research at Yale shows. Increased number of neurons in Tourette's Syndrome patients 02 November 2003 - Yale University Yale researchers have observed an increased number of neurons in the brains of patients with Tourette's Syndrome, a finding that could lead to deeper understanding of how the brain compensates for symptoms of TS. Researchers sequence and analyze the DNA of an ancient parasite 23 October 2003 - Yale University An analysis of the smallest microbial genome ever sequenced supports theories that life may have originated in a hot and fiery primeval earth, according to Yale researchers and collaborators. Racial disparity found in survival rates of children with a common Leukemia 17 October 2003 - Yale University Black, Hispanic and Native American children with Acute Lymphoblastic Leukemia, have worse survival than white and Asian children, even with the availability of modern therapies, Yale researchers report in the October 15 issue of Journal of the American Medical Association. Yale researchers find genetic basis for metastatic cancer 09 October 2003 - Yale University Yale researchers have found genetic mutations that are potential drug targets for metastatic cancer, according to a study published today in Science. Asthmatic children vulnerable to even low levels of ozone 07 October 2003 - Yale University Children with severe asthma are particularly vulnerable to ozone in air pollution even at levels below Environmental Protection Agency standards, Yale researchers report in the October 8 issue of Journal of the American Medical Association. Pregnant asthmatic women can limit newborn complications using beta2 agonists 03 October 2003 - Yale University Pregnant women with asthma can limit newborn complications if they actively manage their asthma with Beta2 agonists, commonly known as bronchodilaters, Yale researchers report in the October issue of Obstetrics and Gynecology. Infants can use previous observations to interpret new ones 29 September 2003 - Yale University Twelve-month-old infants can use previous observations as a basis to understand new interactions, although five-month-olds cannot, according to a Yale study. Discovery of abnormal sugars present in many cancers could lead to new drug targets 22 September 2003 - Yale University Yale researchers have found that as many as 22 kinds of cancers produce abnormal sugars that might help metastasize or spread the disease throughout the body, a discovery that may lead to new drug targets. Estrogen improves short term memory & oral reading in midlife postmenopausal women 09 September 2003 - Yale University Midlife postmenopausal women who received daily treatment with estrogen showed improved oral reading and verbal memory performance, Yale School of Medicine researchers report in the September issue of the journal Menopause. Brain activities differ in problem gamblers 22 August 2003 - Yale University Imaging studies have identified unique brain activity changes in men with pathological gambling when they viewed videotapes about betting on cards or rolling dice at a casino, a Yale study has found. Antipsychotic medication is effective in treating behavior problems in autistic children 21 August 2003 - Yale University One of a newer class of antipsychotic medications was successful and well tolerated for the treatment of serious behavioral disturbances associated with autistic disorder in children ages 5-17, according to a Yale study published this week in the New England Journal of Medicine. Newly invented endometrial function test solves the puzzle of unexplained infertility 14 July 2003 - Yale University A Yale researcher who invented a test to determine whether a woman's endometrium (uterine lining) is healthy and ready for embryo implantation has identified two new biochemical markers that improve assessment of the endometrium. Health problems and financial setbacks risk factors for women and smoking 19 June 2003 - Yale University Women are affected more than men by certain stressful life events, a factor that can contribute to their inability to quit smoking or their decision to resume smoking, according to a new study from Yale researchers. Adolescents are neurologically more vulnerable to addictions 18 June 2003 - Yale University Adolescents are more vulnerable than any other age group to developing nicotine, alcohol and other drug addictions because the regions of the brain that govern impulse and motivation are not yet fully formed, Yale researchers have found. Hyperglycemia common in patients receiving clozapine 30 May 2003 - Yale University Hyperglycemia, which is often a prelude to diabetes, is common in patients taking the antipsychotic drug clozapine, according to Michael Sernyak, associate professor of psychiatry at Yale School of Medicine. Patients with epilepsy more vulnerable to behavioral side effects than people with other brain disorders 28 May 2003 - Yale University Patients with epilepsy may be more likely to experience treatment-related behavioral side effects than patients receiving the same drug for other brain disorders, according to a 4,179-patient case review by a Yale School of Medicine researcher published in the May issue of the journal, Epilepsy and Behavior. Black patients with heart failure have similar quality of care, but better survival than white patients 20 May 2003 - Yale University In the most recent large national study of heart failure care, Yale School of Medicine researchers found that elderly black patients hospitalized for heart failure received similar quality of care as white patients and had higher survival rates than whites up to one year afterwards. Advantech's medical solutions empower medical imaging processing system 16 May 2003 - Advantech UK With the rapid growth of medical information technology, devices and equipment for medical use keep evolving into point-of-care terminals with data processing functionality. The Department of Health in Taiwan, has adopted DICOM 3.0 and HL7 for the telecommunication standard for the 2nd generation Health Information Network and Telehealth. Moreover, with the upgrading of Taiwan's National Health Insurance System, hospitals and other medical institutions are also aggressively advancing their information management systems to meet future needs. Major depression common among people caring for dying loved ones 12 May 2003 - Yale University At least 30 percent of persons caring for a dying loved one suffer from major depressive disorder, a consequence that might be overlooked as care for the terminally ill increasingly shifts from the hospital to the home, according to a Yale researcher. Despite the risks of infection, unprotected oral sex is common among adolescents 07 May 2003 - Yale University Adolescents report high rates of oral sex, more oral sex partners than intercourse partners, and infrequent use of protection from sexually transmitted infections during oral sex, a group of Yale researchers has found. There may be twice as many genes in the human genome than previously thought 21 April 2003 - Yale University A study by Yale University researchers provides preliminary evidence that there may be more than twice as many genes in the human genome than previously predicted. Antipsychotic drug risperidone reduces tics in children and adults with tourette syndrome 17 April 2003 - Yale University A study by Yale researchers suggests that the atypical antipsychotic drug risperidone reduces tic symptoms in children and adults with Tourette syndrome. New Chemical Genetic tool forces cells to target and destroy harmful proteins within those cells 11 April 2003 - Yale University When 'rogue' proteins begin wreaking havoc within cells, the result is diseases such as cancer, heart disease, and inflammatory diseases like rheumatoid arthritis. Chemo-resistant ovarian cancer cells can be destroyed 31 March 2003 - Yale University Yale School of Medicine researchers today released laboratory based data identifying significant new signaling pathways for ovarian cancer and have found that drugs can be used to successfully alter signals to induce cancer cell death. Parents are not at risk of heart attack while watching child being anesthesized 14 February 2003 - Yale University Parents allowed in the operating room while their children were being anesthesized experienced a racing heart rate and sweaty palms, but did not register any abnormalities on their electrocardiograms, a Yale study has found. Twenty percent of people with epilepsy develop drug Rrsistant seizures 06 February 2003 - Yale University Twenty percent of people with epilepsy will eventually develop seizures that are resistant to medication, even if they have experienced long periods with no seizures at all, according to a study led by a Yale researcher. Abdominal and total body fat loss linked to regular exercise 14 January 2003 - Yale University Regular exercise, such as brisk walking, reduces total and intra-abdominal body fat among overweight and obese postmenopausal women, a study by a Yale researcher has found. Yale clinical trial tests new approach for treatment of women with ovarian cancer 19 December 2002 - Yale University Yale School of Medicine researchers are testing a promising new treatment for women with recurrent ovarian cancer, which is the fourth leading cause of cancer-related deaths in women in the United States, affecting one in 100 women. Yale researcher reports new role of cilia in Cystic Fibrosis 18 December 2002 - Yale University cystic Fibrosis, a fatal lung disease striking one in 2,500 people, may be caused by a failure of the cilia to maintain the level of water associated with the mucus in the lungs, causing the natural mucus to thicken and become infected with bacteria, ultimately leading to death, Yale researchers are reporting. Researchers at Yale develop breakthrough drug discovery technology 26 November 2002 - Yale University Researchers at Yale School of Medicine have developed novel digital imaging technology that is capable of pinpointing protein expression patterns in cells that cause diseases such as breast and colon cancer. Results of Autism Study could help researchers with early detection and measuring severity of condition 10 October 2002 - Yale University When individuals with autism view social situations, they focus attention twice as much on the mouths and the bodies of people as on their eyes, Yale researchers report in an Archives of General Psychiatry article. Exercise and strength training could improve physical decline in elderly 02 October 2002 - Yale University Physically frail elderly persons who followed a physical therapy program consisting primarily of balance exercise and strength training saw a 45 percent reduction in disability after seven months, Yale researchers report in the October 3 issue of The New England Journal of Medicine. Clot-busting drugs are often misused 30 September 2002 - Yale University Virtually every stroke patient who was administered a clot-busting medication in clinical practice, and who was included in a study of such cases, was given the medication with deviations from recommended protocols, according to a journal article by a Yale physician. Yale researchers shed light on B cells' involvement in autoimmune diseases like Lupus 25 September 2002 - Yale University Using genetically altered mice, Yale researchers have generated a clearer picture of the origins of B cells and their involvement in autoimmune diseases such as lupus, rheumatoid arthritis and diabetes. Ecological and health effects of the Vietnam war subject of international symposium at Yale 26 August 2002 - Yale University An international conference examining the ecological and health effects resulting from the use of chemical, biological and physical agents during the Vietnam War will take place at Yale University September 13-15, 2002. Research does not support worry that beta blockers cause depression, fatigue and sexual dysfunction 16 July 2002 - Yale University There is no data to support the worry that beta blockers, prescribed following a heart attack to guard against future episodes, commonly cause depression, fatigue and sexual dysfunction, according to a study by Yale researchers published this week in the Journal of the American Medical Association. Yale researchers develop peptide that promotes new growth in laboratory animals with injured spinal cords 29 May 2002 - Yale University Yale researchers have developed a synthetic peptide that promotes new nerve fiber growth in the damaged spinal cords of laboratory rats and allows them to walk better, according to a study published Thursday in the journal Nature. Use of tampons and sexual activity protect women against endometriosis 29 May 2002 - Yale University Using tampons and engaging in sexual activity appears to protect women against developing endometriosis, a painful condition that affects an estimated 10 million American women and often results in infertility, according to research by a Yale physician. Drug gives relief during labor and delivery without uncomfortable numbness 16 May 2002 - Yale University A pain reliever traditionally used for post-operative pain, when diluted and given through an epidural, provides pain relief during labor and delivery without the uncomfortable numbness that makes it difficult for women to push or feel the baby emerge, a Yale study has found. Yale researchers find potential target for treatment and prevention of osteoporosis 16 May 2002 - Yale University By identifying a genetic mutation that causes extremely high bone density in people, Yale researchers have found a potential target for the prevention or treatment of osteoporosis, it was reported Thursday in the New England Journal of Medicine. Brain virus may give clues to causes underlying psychiatric and neurological problems 15 March 2002 - Yale University A Yale researcher tracing a recombinant virus as it entered the brains of laboratory animals found it damaged selective areas and then vanished without a trace, raising questions about possible mental problems caused by undetected viruses. Second patient with multiple sclerosis undergoes groundbreaking surgery at Yale 14 March 2002 - Yale University A 29-year-old man with multiple sclerosis is the second patient to undergo transplantation surgery at Yale in an effort to repair myelin, the protective brain and spinal cord sheath that is destroyed by the disease, Yale researchers have reported. New index developed by Yale researcher to assess the risk of mortality in an elderly population 12 March 2002 - Yale University In order to foster sound health care programs and policies concerning an aging population, a Yale researcher has devised a new index that forecasts which patients are most likely to die within one year after being discharged from the hospital. Yale-designed protocol results in increased diagnoses of problems that are often overlooked in elderly 11 March 2002 - Yale University Yale researchers have designed a geriatric assessment protocol to identify problems that often go undetected in elderly patients, such as depression, incontinence, vision and hearing loss and driving safety issues. Yale researchers reveal how fresh water bacteria that cause Legionnaire's Disease 22 February 2002 - Yale University Yale researchers have revealed how a kind of bacterium that causes Legionnaire's disease can navigate its own course within a human cell by injecting a protein that can steer host cell membranes. Using cocaine during pregnancy may damage developing fetuses causing lifelong learning disabilities 18 February 2002 - Yale University Taking cocaine during pregnancy causes possibly permanent changes in an area of the brain that governs short term memory, leading to symptoms that are very much like attention deficit hyperactivity disorder, Yale researchers have found in two recent studies. Repeated cocaine use impairs region of the brain that governs self control 14 February 2002 - Yale University Taking cocaine impairs the orbitofrontal cortex, an area of the brain responsible for self control and decision making, and the effects persist long after the cocaine use stops, a behavioral study by a Yale researcher and collaborator has found. Dosage appears to be a critical factor in cocaine vaccine 28 January 2002 - Yale University Dosage appears to be a critical factor in the effectiveness of a cocaine vaccine being tested by Yale researchers that is designed to block the euphoria drug abusers experience. Ancients may have been right that Humors are linked to depression 17 January 2002 - Yale University A Yale School of Medicine and Veteran's Affairs Administration study finding that patients with Seasonal Affective Disorder have lower nighttime levels of bilirubin, a bile pigment found in the blood and known by ancient Greek physicians as a 'humor,' lends support to the humoral theories of mood they espoused. Early breast cancer shares some risk factors with advanced breast cancer 16 January 2002 - Yale University Many of the risk factors for more advanced breast cancer also apply to an early form of breast cancer known as breast carcinoma in-situ, according to a study by Yale researchers that is the first large scale study of risk factors for this type of early cancer. Schizophrenia causes complex language processing deficits 14 January 2002 - Yale University Some persons with schizophrenia can remember complex sounds, such as intricate bird songs, but not simple words, providing yet more evidence about the complex nature of the mental illness, a study by Yale researchers has found. Yale study shows rinsing contaminated syringes with water & bleach still effective means of killing HIV 07 January 2002 - Yale University Despite reports to the contrary, clean water and full strength bleach remain an effective means for injection drug users to disinfect syringes contaminated with the HIV virus, a Yale study has found. Acupuncture not effective as a stand-alone treatment for cocaine addiction 02 January 2002 - Yale University Contrary to previous Yale findings showing beneficial effects of acupuncture for treating cocaine addiction, a new large-scale study published in the January 2 issue of the Journal of the American Medical Association, shows that acupuncture is not effective as a primary treatment for this disorder. Yale study finds integrating medical care into mental health services overcomes barriers 21 December 2001 - Yale University Yale investigators have found that integrating primary medical care as part of mental health services for patients with serious mental illness results in significant improvements in their health status and access to medical care. Yale survey finds crying a common experience among medical students & points to its potential value 13 December 2001 - Yale University In an essay published in the Journal of the American Medical Association, a Yale School of Medicine faculty member reported that the vast majority of Yale medical students cried as a result of emotional encounters with patients during their first year of clinical rotations and that the experience of strong emotions can have an important impact on their education as physicians. Brain abscess believed linked to tongue piercing 12 December 2001 - Yale University An abscess detected in the brain of a young woman was believed caused by an infection resulting from having her tongue pierced one month earlier, two Yale physicians have reported. Male & female physicians refer women for cardiac diagnostic procedure less often than men 11 December 2001 - Yale University In the first large national study on the topic, Yale researchers found male and female physicians were more likely to refer men than women for cardiac catheterization, a diagnostic procedure used to assess blood flow to the heart, after a heart attack. New brain cells in adult cortex are unlikely 07 December 2001 - Yale University There is no evidence that adult primates are able to create new neurons in the neocortex, the most sophisticated part of the brain, Yale researchers have found in a study published in the December 7 issue of Science. Long-term treatment with antiepileptic medications can improve quality of life for people with epilepsy 05 December 2001 - Yale University Early improvements in health-related quality of life for epilepsy patients were sustained over several years of treatment with the antiepileptic drug levetiracetam, according to new research presented today by Yale School of Medicine researchers at the 55th American Epilepsy Society annual meeting. Yale's Operation Beating Heart uses telemedicine to screen for causes of sudden death in athletes 29 November 2001 - Yale University Yale surgeon James 'Butch' Rosser, M.D., has devised a portable, cost-effective testing program called 'Operation Beating Heart' to detect potential causes of sudden death in young, competitive athletes. Commonly prescribed sedative may cause delirium symptoms in older hospitalized patients 10 November 2001 - Yale University The frequently prescribed antihistamine and sedative medication diphenhydramine is associated with a 70 percent increased risk of changes in mental status and evidence of delirium symptoms in older, hospitalized patients, Yale researchers report in a recent study. Estrogen therapy does not reduce risk of recurrent stroke or death 26 October 2001 - Yale University Despite many observational studies linking hormone replacement therapy to reduced risk of cardiovascular disease and possibly stroke, Yale researchers have found in a new study that HRT does not reduce the risk of a second stroke or death in women with cerebrovascular disease. Blood transfusions drastically reduce death in anemic elderly heart attack patients 24 October 2001 - Yale University Yale researchers have found that giving blood transfusions to anemic elderly heart attack patients significantly improves the survival rate for that group. Animal-based nutrients linked with higher risk of stomach and esophageal cancers 15 October 2001 - Yale University Yale School of Medicine researchers have found that a diet high in cholesterol, animal protein and vitamin B12 is linked to risk of a specific type of cancer of the stomach and esophagus that has been increasing rapidly. Stable methadone patients can successfully continue treatment in a primary care physician's office 10 October 2001 - Yale University When stable methadone patients, who were formerly addicted to heroin and other narcotics, switch from a narcotic treatment program to a physician's office for continuing methadone maintenance treatment, they become more accepting of the treatment and they continue to do well, Yale researchers have found. Yale researchers develop new molecule that eradicates cancer by destroying tumor blood vessels 02 October 2001 - Yale University Researchers at Yale have developed a new molecule they call 'icon' that targets blood vessels in tumors for destruction by the immune system without harming vessels in normal tissues. HIV patients more likely to accept a drug Regimen if they trust in the physician 24 September 2001 - Yale University A study of HIV-infected prisoners shows that they are more likely to accept antiretroviral therapy if they have trust in the treatment, their physicians and in medical institutions, highlighting the important role that trust plays in HIV therapy, Yale researchers report. T cells can halt development of skin cancer 21 September 2001 - Yale University In a study published in today's issue of Science, Yale researchers show that gamma-delta T cells, a special kind of white blood cell found in the skin, are critical in the defense against skin cancer development. Restricted activity in the elderly is common, yet many do not seek medical care 03 September 2001 - Yale University Restricted activity-staying in bed for at least half a day or cutting down on activities because of an illness or injury-affects about 76 percent of elderly people, yet many do not seek medical attention, Yale researchers report in a new study. Yale researchers discover a genetic cause of high blood pressure 09 August 2001 - Yale University Researchers at Yale studying a rare inherited form of hypertension have discovered mutations in two different genes that can cause this disease, clearing the way for new medications to treat both the rare and common forms of high blood pressure. Herb used to treat migraine headaches could be used to develop new anti-inflammatory drugs 08 August 2001 - Yale University Yale researchers have shown for the first time that a component of the medicinal herb feverfew targets a protein called IkappaB Kinase and halts that protein's role in the inflammation process. ADHD and tic disorders in children corrected with Guanfacine 31 July 2001 - Yale University Children with attention deficit hyperactivity disorder and tic disorders showed a 37 percent improvement when they took the medication guanfacine, an alternative to drugs like Ritalin, which can worsen tics, Yale researchers found in a new study published in the July issue of American Journal of Psychiatry. Groundbreaking transplantation surgery at Yale attempts to repair central nervous system in MS patients 23 July 2001 - Yale University Researchers at Yale School of Medicine have performed the first central nervous system transplantation to repair the myelin-forming cells in a woman with multiple sclerosis. People with sleep apnea at higher risk of stroke 22 June 2001 - Yale University People with sleep-related breathing disorders, such as habitual snoring and sleep apnea, are at higher risk of suffering a stroke, according to a study by a Yale researcher published in the June issue of the journal Stroke. Breast cancer risk minimized by breastfeeding 18 June 2001 - Yale University Women who breastfeed their children, particularly if the first child is breastfed for more than 13 months, have a reduced risk of breast cancer, according to a study by a Yale researcher and published in the British Journal of Cancer. The study involving Conecticut women showed a stronger association between reduced risk of breast cancer and women who breastfed their children. The protection also was more pronounced in pre-menopausal years rather than following menopause. Antibiotic treatment of tick bites prevents only 20 percent of Lyme Disease cases 14 June 2001 - Yale University Even if every patient who noticed they had a tick bite received prompt antibiotic treatment and if it were 100 percent effective in preventing Lyme disease, it would only prevent 20 percent of the total Lyme disease cases, Yale researcher Durland Fish said. Poor quality medical care key factor in high death rate among mentally ill heart attack patients 14 June 2001 - Yale University Poor medical care may be key to explaining a substantial part of the high death rate among patients with mental disorders after myocardial infarction or heart attack, Yale researchers have found. Recently-discovered protein could be key to understanding and preventing type-2 diabetes 31 May 2001 - Yale University A protein called Akt2 or Protein Kinase B plays an important role in maintaining glucose balance, possibly leading to a drug target for preventing Type-2 diabetes, Yale researchers report in a study published in the June 1 issue of Science. Leptin's effect on the brain's body weight regulation system is more complex than previously thought 23 May 2001 - Yale University Leptin, a hormone known for its hunger-blocking effect on the brain, operates in a more complex way than previously thought, researchers from Yale and The Vollum Institute find, possibly leading to development of drugs that can better interfere with appetite and eating behavior to fight obesity and diabetes. Down Syndrome detection rate improves with Yale researcher's new formula 22 May 2001 - Yale University Almost 80% of Down syndrome cases can be detected with a new non-invasive formula using a ratio of skin thickness and limb measurements, Yale researchers report in a study published in the May issue of American Journal of Obstetrics and Gynecology. Use or non-use of Beta Blockers provides clues for improving healthcare quality in hospitals 22 May 2001 - Yale University Although it is well documented that using beta blockers is effective in preventing a subsequent heart attack or death, not all hospitals are prescribing them widely for complicated internal reasons, a study by researchers at Yale concludes. Racial disparities exist in diagnostic procedure for heart attack patients 18 May 2001 - Yale University In one of the largest national studies on the topic, Yale researchers have demonstrated a marked racial difference in the rate of cardiac catheterization, a diagnostic procedure used to assess heart function after a myocardial infarction or heart attack. Smoking cigarettes, cigars, pipes or using snuff or chewing tobacco does not cause brain cancer 09 May 2001 - Yale University Although cigarette smoking and use of other tobacco products are considered to be the greatest single source of human exposure to certain carcinogens, they do not appear to cause brain cancer, a Yale investigation has found. Yale researchers create topical estrogen ahat alleviates sexual dysfunction in menopausal women 09 May 2001 - Yale University To alleviate vaginal dyspareunia or dryness, a painful symptom of menopause that causes sexual dysfunction, Yale researchers have created a topical estrogen that eliminates side effects of conventional estrogen and that in the future could also alleviate some symptoms of aging skin. Study raises questions about relationship between sudden infant death syndrome 02 May 2001 - Yale University The use of home monitors to detect prolonged cessation of breathing or a slower than normal heart rate in infants are not an effective means of preventing sudden infant death syndrome, a study by a Yale researcher has found. Blood flow to brain indicates when recovering cocaine addicts are able to bBenefit from talk therapy 24 April 2001 - Yale University Measuring blood flow to the brain may be a useful way to determine when a recovering cocaine addict is able to benefit from cognitive behavior therapy as a treatment for cocaine addiction, a Yale researcher has found. New vaccine for chickenpox shown to be highly effective in study by Yale researchers 28 March 2001 - Yale University The vaccine for chickenpox, approved by the U.S. Food and Drug Administration in 1995, is highly effective in preventing chickenpox or minimizing the severity of the disease in children, according to a study by researchers at Yale. Chronic depression hastens disease progression and mortality among women with HIV 21 March 2001 - Yale University Women who are HIV-positive and depressed are twice as likely to die as women who are HIV-positive but experiencing limited or no depressive symptoms, a study by a Yale researcher shows. Men with chronic Schizophrenia lose brain volume faster 20 March 2001 - Yale University Men with chronic schizophrenia lose brain volume at a faster rate than the normal aging changes seen in men without the mental illness, a study by a researcher at Yale shows. Women under age 60 have higher mortality rates than men in two years following a heart attack 02 March 2001 - Yale University Women under the age of 60 have a higher risk of dying than men under 60 in the two years after they suffer a heart attack, a study by a Yale researcher and collaborators shows. Cutting inpatient psychiatric care does not reduce overall success rate for posttraumatic stress 14 February 2001 - Yale University When VA hospitals cut inpatient psychiatric care, there is no overall reduction in effective care and clinical outcomes for posttraumatic stress disorder patients, Yale researchers report in the February issue of 15 Medical Care. Yale researchers find all of the gene targets for a protein 26 January 2001 - Yale University Using new DNA chip technology, Yale researchers have identified virtually all of the gene targets of some key proteins, known as transcription factors. Transcription factors tell a cell whether it will be, for example, a muscle cell or a nerve cell. They determine the fate of a cell by 'turning on' a particular assortment of genes within the cell and they can control cell proliferation. Breast cancer risk reduced by 50 percent by breastfeeding for two or more years 25 January 2001 - Yale University Breastfeeding for two or more years reduces a woman's risk of developing breast cancer by 50 percent, according to a study conducted by a Yale researcher among women in China. Yale researcher finds new clue to what blocks nerve fibers from regrowing Following spinal cord injury 18 January 2001 - Yale University Researchers are one step closer to reversing brain and spinal cord injuries with the discovery of another molecule in a pathway that prevents axon regeneration, a Yale researcher says. Salmonella in combination with radiation effective against cancer tumors 10 January 2001 - Yale University A study of melanoma tumors by Yale researchers shows that Salmonella injections in combination with radiation therapy could provide a promising new cancer therapy. Interpretations of brain activity based on cognitive theories fail to recognize background neuronal firing