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News

Carnegie Mellon research may lead to improvements for drug industry

Carnegie Mellon Universtity : 17 March, 2003  (Technical Article)
Carnegie Mellon University researchers Andy Gellman, head of chemical engineering, and David Sholl, an assistant professor of chemical engineering, are developing new solid surfaces that will help drug makers separate 'left-handed' and 'right-handed' molecules.
Carnegie Mellon University researchers Andy Gellman, head of chemical engineering, and David Sholl, an assistant professor of chemical engineering, are developing new solid surfaces that will help drug makers separate 'left-handed' and 'right-handed' molecules.

The design and separation of left- and right-handed molecules in drugs has tremendous impact on many drugs. For example, thalidomide was first marketed in the early 1950s for respiratory infections. Thalidomide was later prescribed in concert with chemicals as a sedative and treatment of morning sickness.

While the left-handed drug had a proven therapeutic track record, the right-handed molecules of the drug were eventually linked to physical birth defects. The research is vital for developing more economical and purer drugs for consumers and physicians.
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