Free Newsletter
Register for our Free Newsletters
Newsletter
Zones
Advanced Composites
LeftNav
Aerospace
LeftNav
Amorphous Metal Structures
LeftNav
Analysis and Simulation
LeftNav
Asbestos and Substitutes
LeftNav
Associations, Research Organisations and Universities
LeftNav
Automation Equipment
LeftNav
Automotive
LeftNav
Biomaterials
LeftNav
Building Materials
LeftNav
Bulk Handling and Storage
LeftNav
CFCs and Substitutes
LeftNav
Company
LeftNav
Components
LeftNav
Consultancy
LeftNav
View All
Other Carouselweb publications
Carousel Web
Defense File
New Materials
Pro Health Zone
Pro Manufacturing Zone
Pro Security Zone
Web Lec
Pro Engineering Zone
 
 
 
News

New alternative for CIP process users

Greene Tweed & Co Benelux BV : 28 May, 2006  (New Product)
Pharmaceutical companies who employ CIP processes have had to make tough decisions-such as choosing the proper elastomer-for some of their most demanding cleaning programs. Recent tests in a CIP system at Pfizer's Littitz, Pa., facility point to Greene, Tweed's Fluoraz, a TFE/P fluoroelastomer, as the ideal elastomer for withstanding the extreme conditions found in CIP processes.
Pharmaceutical companies who employ CIP processes have had to make tough decisions-such as choosing the proper elastomer-for some of their most demanding cleaning programs. Recent tests in a CIP system at Pfizer's Littitz, Pa., facility point to Greene, Tweed's Fluoraz, a TFE/P fluoroelastomer, as the ideal elastomer for withstanding the extreme conditions found in CIP processes.

Unlike EPDMs that have a limited temperature range, FKMs that can't survive the harshness of potassium hydroxide, or PTFEs that leak, Fluoraz is a true base-resistant elastomer. Testing at the Pfizer site showed FKM gaskets virtually destroyed by Steris's CIP 100 in just 30 minutes at 120C (248F). Additionally, concerns about potential extractables entering creams and ointments troubled Pfizer. Test results showed that 94 percent of the Viton seals (16 out of 17) used by Pfizer were damaged at operating temperatures and normal cleaning flow rates while Greene, Tweed's Fluoraz gaskets showed no signs of damage. Fluoraz allows pharmaceutical companies to increase the level of cleanliness without having to be concerned about degrading their elastomer seals, or the possible contamination resulting from such seal degradation. CIP systems typically include a caustic wash and acid flush (usually phosphoric acid) followed by a buffer rinse. Not one of these solutions affects Fluoraz's performance.

Tim Duzick, Greene, Tweed's pharmaceutical product manager, remarked, 'Many end users, such as Pfizer, are unaware that there is a safe, reliable elastomer that won't degrade in harsh environments common in CIP applications. Fluoraz gives users a true CIP-resistant elastomer-something they never had before.'

Fluoraz combines the steam and caustic resistance of EPDM with the heat resistance of a fluoroelastomer, providing the ideal sealing solution for steam-in-place and clean-in-place applications. Fluoraz is well suited for pharmaceutical companies who are looking to use higher temperature steam and stronger caustic cleaning agents but have been struggling to find an elastomer able to outlast these harsh conditions.
Bookmark and Share
 
Home I Editor's Blog I News by Zone I News by Date I News by Category I Special Reports I Directory I Events I Advertise I Submit Your News I About Us I Guides
 
   © 2012 NewMaterials.com
Netgains Logo