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News

Shortcut advancing Bovine research

CSIRO : 25 September, 2003  (Technical Article)
CSIRO Livestock Industries has launched an interactive database which enables researchers to dramatically reduce the time and other resources it will take to unravel the mysteries of the bovine genome.
CSIRO Livestock Industries has launched an interactive database which enables researchers to dramatically reduce the time and other resources it will take to unravel the mysteries of the bovine genome.

'The release of the Interactive Bovine In Silico SNP database provides researchers with easy access to a huge body of information about the bovine genome while also enabling them to contribute new data crucial to the work of others,' says CLI research scientist, Dr Rachel Hawken.

The database has rationalised the vast spectrum of around 324,000 publicly available bovine sequences to identify 17,000 Single Nucleotide Polymorphisms, 70 per cent of which are estimated to be genuine.

'If a researcher is interested in a gene that may have an influence on a commercial cattle trait they can search IBISS for that gene and, upon finding it, the database will then pull up the bovine DNA sequence and predicted amino acid sequence, gene structure and SNP for that gene, all in a single page,' Dr Hawken says.

'This means genome researchers don't have to spend large amounts of time and money locating and relating SNP information from multiple sources. What would normally take half a day to accomplish can now be achieved within 30 minutes using IBISS.'

The web-based database is freely available to researchers through a 'login' system.

'We have set up IBISS to be a continuously updating resource for bovine researchers, it is a two-way system,' Dr Hawken says.

'We provide the data free of charge and in return we ask that, if a user has sequence data which validate or deny any putative SNP those sequences be submitted for incorporation into IBISS.

'The SNP validation data we receive from users can be withheld from publication for a period, but ultimately will be incorporated into IBISS for the benefit of all users.' Dr Hawken says.
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